NHMRC Research Fellowship 2009 - McConville

Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase is a potential drug target

SM Allen, EE Lim, E Jortzik, J Preuss, HH Chua, JI MacRae, S Rahlfs, K Haeussler, MT Downton, MJ McConville, K Becker, SA Ralph

2015-10-01

The malarial parasite Plasmodium falciparum is exposed to substantial redox challenges during its complex life cycle. In intraeryt..

Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages

T Naderer, J Heng, EC Saunders, J Kloehn, TW Rupasinghe, TJ Brown, MJ McConville

2015-01-01

Leishmania parasites replicate within the phagolysosome compartment of mammalian macrophages. Although Leishmania depend on sugars..

Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

EC Saunders, WW Ng, J Kloehn, JM Chambers, M Ng, MJ McConville

2014-01-01

Leishmania parasites alternate between extracellular promastigote stages in the insect vector and an obligate intracellular amasti..